The Risk Factor for Ovarian Cancer

Knowing the risk factors for ovarian cancer can keep you one step ahead. Knowing what is and isn’t linked to ovarian cancer help put us at ease because the unknown is always the scary. Researchers have discovered certain factors that change a woman’s likelihood of developing ovarian cancer. Read about some of the risk factors below.

Age

The risk of developing ovarian cancer gets higher with age. Ovarian cancer is rare in women younger than 40. Most ovarian cancers develop after menopause. Half of all ovarian cancers are found in women 63 years of age or older.

Obesity

Various studies have looked at the relationship of obesity and ovarian cancer. Overall, it seems that obese women (those with a body mass index of at least 30) have a higher risk of developing ovarian cancer.

Reproductive history

Women who have been pregnant and carried it to term have a lower risk of ovarian cancer than women who have not. The risk goes down with each full-term pregnancy. Breastfeeding may lower the risk even further.

Birth control

Women who have used oral contraceptives (also known as birth control pills or the pill) have a lower risk of ovarian cancer. The lower risk is seen after only 3 to 6 months of using the pill, and the risk is lower the longer the pills are used. This lower risk continues for many years after the pill is stopped.

A recent study found that the women who used depot medroxyprogesterone acetate (DMPA or Depo-Provera CI^®), an injectable hormonal contraceptive had a lower risk of ovarian cancer. The risk was even lower if the women had used it for 3 or more years.

Gynecologic surgery

Tubal ligation (having your tubes tied) may reduce the chance of developing ovarian cancer by up to two-thirds. A hysterectomy (removing the uterus without removing the ovaries) also seems to reduce the risk of getting ovarian cancer by about one-third.

Fertility drugs

In some studies, researchers have found that using the fertility drug clomiphene citrate (Clomid^®) for longer than one year may increase the risk for developing ovarian tumors. The risk seemed to be highest in women who did not get pregnant while on this drug. Fertility drugs seem to increase the risk of the type of ovarian tumors known as "low malignant potential" (described in the section, "What is ovarian cancer?"). If you are taking fertility drugs, you should discuss the potential risks with your doctor. However, women who are infertile may be at higher risk (compared to fertile women) even if they don’t use fertility drugs. This might be in part because they haven't given birth or used birth control pills (which are protective). More research to clarify these relationships is now underway.

Estrogen therapy and hormone therapy

Some recent studies suggest women using estrogens after menopause have an increased risk of developing ovarian cancer. The risk seems to be higher in women taking estrogen alone (without progesterone) for many years (at least 5 or 10). The increased risk is less certain for women taking both estrogen and progesterone.

Unfortunately risk factors don’t tell us everything we need to know about diseases. And having one even several risk factors does not automatically mean you’ll get the disease. To learn about more risk factors follow the link to read the full article from American Cancer Society:  http://bit.ly/1r9S8d3