Monday, March 16, 2015

Ovarian Cancer Prevention Takes the Spotlight



A recent video at Medscape shows Dr. George Lundberg explaining how ovarian cancer works, as well as a new method that could help prevent it. In the transcript for the video, Dr. Lundberg explores an idea that could help prevent ovarian cancer in women. He also explores how this method might be tested. Here is the beginning of his interview?

“Hello. I am Dr George Lundberg and this is At Large at Medscape.

The best way to deal with a potentially fatal cancer is to prevent it. In order to prevent a cancer, one must understand either the etiology or the pathogenesis so as to design an intervention.

Doctor, what do you know about cancer of the ovary?

Frequency? About 22,000 cases per year in the United States.[1]

Incidence? 12/100,000 women per year.[1]

Pathology? There are many types and subtypes by gross appearance, histology, immunohistochemistry, and genomics.

Do you know the etiology? No one does, except for a few cancer types that are from genetic mutations or are familial.

Prognosis? Depends mostly on type.

How is the diagnosis made? By tissue sampling, often late.

Does screening work? Unfortunately, no.

How to treat? Surgical removal, if possible; chemotherapy.

Outcomes? Poor for those far advanced at diagnosis, which is most. More than 14,000 American women with ovarian cancer die annually,[1] for a death percentage of 65%. Not good.

Have we been making progress? Not really. Death rates have not changed much in some 50 years.”

View the original video to learn more: http://www.medscape.com/viewarticle/840816

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